World leaders from nine EU countries and southern states are making their way to Malta for the MED9 summit.
Among the topics to be discussed are immigration as well as climate change, with Prime Minister Robert Abela greeting leaders as they arrive on the islands.
Among them are European Commission president Ursula von Der Leyen and the president of the European Council, Charles Michel.
Ahead of the summit, von der Leyen visited the Nadur Primary School, meeting Minister for Gozo Clint Camilleri in the process.
French President Emmanuel Macron and Italian Prime Minister Giorgia Meloni are also among the leaders coming to the island, both of whom were already in talks about the migration topic.
Organised crime, human trafficking and other topics are also on the agenda, with road closures having been announced for areas in Valletta ahead of the summit by police.
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