In a historic medical first, Maryland doctors have successfully transplanted a genetically modified pig’s heart into a human patient in a last-ditch effort to save his life. Doctors at the University of Maryland medical centre stated on Monday that the patient was doing well three days after the highly experimental surgery. However, it is too soon to know if the operation has been a success.
However, whether a scientific victory or not, the transplant marks a massive step ahead in the quest to one day use animal organs to conduct life saving operations. Doctors said the transplant shows a heart from a genetically modified animal can function in the human body without immediate rejection.
David Bennett, the 57-year-old patient, knew that there was no guarantee the experiment would work. However, he was dying, ineligible for a human heart transplant and had no other option. He described it as a shot in the dark which could potentially just have worked. On Monday, the patient was breathing on his own while still connected to a heart-lung machine to help his new heart. The next few weeks will be critical as Bennett recovers from the surgery.
Scientific director of the university’s animal-to-human transplant program Dr Muhammad Mohiuddin said that if this works, there will be an endless supply of these organs for patients who are suffering. Previous transplants from animals failed, particularly one in 1984 wherein a dying infant lived 21 days with a baboon heart.
What could be different this time is the fact that the pig heart underwent gene-editing to be more suitable in a human body. Doctors are still cautioning it as a tentative step into exploring whether this type of procedure, called xenotransplantation, finally works. What do you think?
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